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Download Bioorganometallic Chemistry: Applications in Drug Discovery, by Gérard Jaouen, Michèle Salmain PDF

By Gérard Jaouen, Michèle Salmain

An updated reference reflecting the numerous advances and critical breakthroughs made during this rising self-discipline over the past decade.
As such, the publication presents an outline of the most recent advancements and destiny tendencies within the box, targeting such functions because the improvement of doubtless lively organometallic medicinal drugs opposed to incurable illnesses, in addition to in such parts as catalysis, power, analytical chemistry, and imaging.
The well known editor, who validated the time period "bioorganometallics", and his foreign workforce of specialists have prepare a invaluable source for researchers in organometallic, inorganic, medicinal, and biochemistry.

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Extra resources for Bioorganometallic Chemistry: Applications in Drug Discovery, Biocatalysis, and Imaging

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Compound 54 inhibits CA II, CA XII, and CA XIV in the low nanomolar range similar to the known CA inhibitor acetazolamide (AZA), which is an approved drug against a range of conditions including glaucoma, abnormal retention of fluids, epileptic seizures, and so on [176]. 26, 54 has a much more pronounced selectivity pattern over the range of the 12 CA isozymes studied in this work compared with AZA. 4). 26 Comparison of the inhibition constants of 54 and AZA over a range of isozymes of hCAs. 27 Crystal structure of complex 57  hCA II (PDB code: 3RJ7).

2009) Biochemistry, 48, 5187–5198. , and 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 Marmorstein, R. (2008) ACS Chem. , 3, 305–316. , and Meggers, E. (2004) Org. , 6, 521–523. , and Meggers, E. (2010) Angew. , Int. , 49, 3839–3842. , and Meggers, E. (2012) Chem. , 48, 1863–1865. , and Meggers, E. , 41, 9337–9348. S. (2012) Inorg. Chim. Acta, 393, 84–102. , and Meggers, E. (2007) Inorg. , 46, 2944–2946. , and Meggers, E. (2012) Eur. J. Inorg. , 2012, 813–821. , and Meggers, E. (2012) Inorg. Chim.

And Marmorstein, R. (2009) Biochemistry, 48, 5187–5198. , and 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 Marmorstein, R. (2008) ACS Chem. , 3, 305–316. , and Meggers, E. (2004) Org. , 6, 521–523. , and Meggers, E. (2010) Angew. , Int. , 49, 3839–3842. , and Meggers, E. (2012) Chem. , 48, 1863–1865. , and Meggers, E. , 41, 9337–9348. S. (2012) Inorg. Chim. Acta, 393, 84–102. , and Meggers, E. (2007) Inorg. , 46, 2944–2946. , and Meggers, E. (2012) Eur. J. Inorg. , 2012, 813–821. , and Meggers, E.

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